Prevention of stroke and systemic embolism (SEE) in adult patients with nonvalvular atrial fibrillation (NVAF) who have one or more of the following risk factors:
· Previous stroke, transient ischemic attack or systemic embolism
· Left ventricular ejection fraction < 40%
· Symptomatic heart failure, NYHA cardiac function grade ≥ 2
· Age ≥ 75
· Age ≥ 65 years, with any of the following conditions: diabetes, coronary artery disease, or hypertension
Treatment of acute deep vein thrombosis (DVT) and/or pulmonary embolism (PE), and prevention of related deaths.
Prevention of recurrent deep vein thrombosis (DVT) and/or pulmonary embolism (PE) and related deaths.